The mixture of inulin and pomegranate extract is also the natural enemy of cholesterol.

Recently, a study conducted by the University of California, Los Angeles, showed that pomegranate extract (PomX) mixture rich in polyphenols and inulin polysaccharides can effectively alleviate the changes in lipid metabolism caused by high-fat diet and reduce individual cholesterol content. At present, the research results have been published in the journal 0x9A8B. It is reported that this study is the first to evaluate the cholesterol lowering effect of a mixture of pomegranate extract and inulin, and no health effect of this combination has been found before.

As we all know, pomegranate itself is a very healthy food, which can be said to be full of babies. Pomegranate peel contains polyphenols, such as ellagic acid and glucoside; Pomegranate seeds contain polyunsaturated fatty acids, including pomegranate acid, palmitic acid and linoleic acid. Pomegranate pulp contains a variety of phenolic compounds and flavonoids, which has a strong antioxidant capacity. At present, pomegranate polyphenols are mostly used in dietary supplements and cosmetics on the market, and the main health claim is antioxidant. Compared with pomegranate, inulin has a high reputation in the health industry circle, with the dual attributes of dietary fiber and prebiotics. Many manufacturers are very optimistic about the market application of inulin fiber, including dairy products, snacks, beverages, dietary supplements, etc.

Inulin Pomegranate Extract, Super Combination

The researchers divided the 6-7 week old male mice into four groups, all of which adopted a high fat and high sugar diet. The mice in the control group were not fed with other additional ingredients. The mice in the second group were fed with pomegranate extract (0.25%), the mice in the third group were fed with inulin (9%), and the mice in the fourth group were fed with pomegranate extract and inulin mixture. Therefore, the main purpose of this study was to evaluate the effects of pomegranate extract and inulin mixture on cholesterol and lipid metabolism.

Four weeks later, the researchers found that the mixture of pomegranate extract and inulin can reduce the total cholesterol in the liver serum of mice, which is better than the health effect of taking inulin or pomegranate extract alone. Pomegranate extract can increase the gene expression of Cyp7a1 and Cyp7b1, two key regulatory factors in the bile acid synthesis pathway, and reduce the content of triglycerides in the liver. Inulin can reduce the gene expression of Srebf2 and Hmgcr, the key regulators of cholesterol de novo synthesis, and significantly increase the excretion of total bile acid and total neutral sterol in feces.

In addition, compared with the high-fat/sucrose diet, the mixture of pomegranate extract and inulin can significantly reduce the weight of liver and lipid, which also involves changes in intestinal microbial metabolism. The specific mechanism of this study is still unclear. In the future, it is necessary to further analyze the relevant mechanisms of cholesterol reabsorption and intestinal cholesterol synthesis, as well as the problems of intestinal microecology, which will help increase people's understanding of pomegranate extract and inulin in regulating the cholesterol balance in the whole body.

Inulin composite products attract attention. The turmoil on intestinal health in the industry has not stopped, and the whole market has also begun to shift from the core role of intestinal health "probiotics" to the more concerned probiotic food "prebiotics", because intestinal microorganisms will eat intestinal mucosa and mucus without dietary fiber. Inulin, as a high-quality prebiotic, its new role has also attracted the attention of the market. Many end products have added this raw material, from infant milk powder to food and beverage to nutritional health products.

As a food for intestinal microorganisms, the relationship between prebiotics and intestinal health has been relatively clear. At present, probiotics are the most used functional raw materials for inulin composite products on the market. The function of inulin fiber is not only limited to intestinal health, but also has a very broad application prospect in replacing sugar and fat. Inulin composite products continue. The health care effects of pomegranate extract and inulin provide new ideas and development space for inulin composite products.

Of course, the market popularization of inulin fiber is based on the scientific and rigorous experimental basis and the health claims of authoritative institutions. In 2015, the European Food Safety Agency (EFSA) approved the health claim that chicory fiber can maintain normal intestinal function, and in 2016 approved the health claim that chicory fiber can reduce blood sugar. As early as 2000, the FDA of the United States has recognized it as GRAS, and China has also approved it as a new resource food. The health claims and experimental research of inulin fiber continue